Skye's father Cal is back and he has brought some friends. Somehow Cal has found or created a team of super villains who are bent Coulson's destruction.
Among this group is the Marvel villian Angar the Screamer.
David A Angar - Known in the comics as Angar the Screamer. Who has a voice that can create hallucinogenic effects to those who hear it. His scream can cause permanent hearing loss and insanity.
Francis Noche - Unknown - There was a man named Francis who became a high powered villain named Ajax. He is part of the Weapon X and Deadpool's origin story.
Karla Faye Gideon- An abused wife who appears in the Daredevil comics - This version sports what looks to be metal claws.
Wendell Levi - Unknown
"One of Us" - Cal seeks revenge on Coulson by assembling a team of Super Villains to destroy S.H.I.E.L.D. Meanwhile, May calls on renowned Dr. Andrew Garner (Blair Underwood), her charismatic ex-husband, with a crisis that threatens to tear the team apart, on "Marvel's Agents of S.H.I.E.L.D.," Tuesday, March 17 (9:00-10:00 p.m., ET) on the ABC Television Network.
"Marvel's Agents of S.H.I.E.L.D." stars Clark Gregg as Director Phil Coulson, Ming-Na Wen as Agent Melinda May, Brett Dalton as Grant Ward, Chloe Bennet as Agent Skye, Iain De Caestecker as Agent Leo Fitz, Elizabeth Henstridge as Agent Jemma Simmons, Nick Blood as Lance Hunter and Adrianne Palicki as Bobbi Morse.
Guest starring are Henry Simmons as Alphonso "Mack" Mackenzie, Kyle Maclachlan as The Doctor/Cal, Jamie Harris as Gordon, Blair Underwood as Dr. Andrew Garner, Drea De Matteo as Karla Faye Gideon, Ric Sarabia as Wendell Levi, Geo Corvera as Francis Noche, Jeff Daniel Phillips as David A. Angar, Gregg Martin as student, Jack Kennedy as security guard and Jamal Duff as John Bruno.
Marvels Agent of Shield speculation HUB
What are Bobbi and Mack hiding?
"Who you really are" Promo and Analysis